Synergistic Role of Protein Phosphatase Inhibitor 1 and SERCA2a in the Acquisition of the Contractile Phenotype of Arterial Smooth Muscle Cells
نویسندگان
چکیده
Cardiovascular Research Center. Mount Sinai School of Medicine, New York, NY; Inserm UMRS 956, Université Pierre et Marie Curie-Paris 6, Paris, France; LIA/Transatlantic Cardiovascular Research Center Université Pierre et Marie Curie/Mount Sinai School of Medicine, New York, NY; INSERM U770, University Paris Sud, Le Kremlin-Bicêtre, France; PECMV-Université Pierre et Marie Curie-Paris, Paris, France; University of Cincinnati, Cincinnati, OH
منابع مشابه
Synergistic role of protein phosphatase inhibitor 1 and sarco/endoplasmic reticulum Ca2+ -ATPase in the acquisition of the contractile phenotype of arterial smooth muscle cells.
BACKGROUND Phenotypic modulation or switching of vascular smooth muscle cells from a contractile/quiescent to a proliferative/synthetic phenotype plays a key role in vascular proliferative disorders such as atherosclerosis and restenosis. Although several calcium handling proteins that control differentiation of smooth muscle cells have been identified, the role of protein phosphatase inhibitor...
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